Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence.

To examine the relationship between macrophage tropism and neurovirulence, macaques were inoculated with two recombinant hybrid viruses derived from the parent viruses SIVmac239, a lymphocyte-tropic, non-neurovirulent clone, and SIV/17E-Br, a macrophage-tropic, neurovirulent virus strain. The first...

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Main Authors: Mankowski, J L, Flaherty, M T, Spelman, J P, Hauer, D A, Didier, P J, Amedee, A M, Murphey-Corb, M, Kirstein, L M, Muñoz, A, Clements, J E, Zink, M C
Format: Artigo
Jezik:Inglês
Izdano: 1997
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC191864/
https://ncbi.nlm.nih.gov/pubmed/9223498
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