Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus.

To identify the molecular determinants of neurovirulence, we constructed an infectious simian immunodeficiency virus (SIV) molecular clone, SIV/17E-Fr, that contained the 3' end of a neurovirulent strain of SIV, SIV/17E-Br, derived by in vivo virus passage. SIV/17E-Fr is macrophage tropic in vitro a...

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Publicado en:	J Virol
Autores principales:	Flaherty, M T, Hauer, D A, Mankowski, J L, Zink, M C, Clements, J E
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1997
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9223467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.8.5790-5798.1997
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