A monoclonal antibody (12G5) directed against CXCR-4 inhibits infection with the dual-tropic human immunodeficiency virus type 1 isolate HIV-1(89.6) but not the T-tropic isolate HIV-1(HxB).

We used a monoclonal antibody (12G5) directed against an extracellular domain of CXCR-4 to investigate the role of this receptor in infection of immortalized lymphoid cell lines, peripheral blood mononuclear cells (PBMCs), and primary brain microglia with a dual-tropic strain of human immunodeficien...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Strizki, J M, Turner, J D, Collman, R G, Hoxie, J, González-Scarano, F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5678-5683.1997
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