D-Arg[Hyp3-Thi5-D-Tic7-Tic8]-bradykinin, a potent antagonist of smooth muscle BK2 receptors and BK3 receptors.

D-Arg[Hyp3-Thi5-D-Tic7-Tic8]-bradykinin (NPC 16731) inhibited bradykinin (BK) binding and BK-induced contraction in guinea-pig ileum, being markedly more potent than D-Phe7-BK analogues as a BK2 receptor antagonist. In isolated trachea NPC 16731, unlike other BK2 antagonists, inhibited BK binding an...

Full description

Saved in:
Bibliographic Details
Main Authors: Farmer, S. G., Burch, R. M., Kyle, D. J., Martin, J. A., Meeker, S. N., Togo, J.
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917984/
https://ncbi.nlm.nih.gov/pubmed/1649657
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items