Increase in the frequency of hepadnavirus DNA integrations by oxidative DNA damage and inhibition of DNA repair.

Persistent hepadnavirus infection leads to oxidative stress and DNA damage through increased production of toxic oxygen radicals. In addition, hepadnaviral DNA integrations into chromosomal DNA can promote the process of hepatocarcinogenesis (M. Feitelson, Clin. Microbiol. Rev. 5:275-301, 1992). Whi...

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書目詳細資料

發表在:	J Virol
Principais autores:	Petersen, J, Dandri, M, Bürkle, A, Zhang, L, Rogler, C E
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1997
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188618/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5455-5463.1997
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