Human immunodeficiency virus type 1 nucleocapsid protein promotes efficient strand transfer and specific viral DNA synthesis by inhibiting TAR-dependent self-priming from minus-strand strong-stop DNA.

During the first strand transfer in reverse transcription, minus-strand strong-stop DNA [(-) SSDNA] is annealed to the 3' end of the acceptor RNA in a reaction mediated by base-pairing between terminal repeat sequences in the RNA and their complement in the DNA. The large stem-loop structure in the...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Guo, J, Henderson, L E, Bess, J, Kane, B, Levin, J G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188585/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5178-5188.1997
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