Human immunodeficiency virus type 1 nucleocapsid protein promotes efficient strand transfer and specific viral DNA synthesis by inhibiting TAR-dependent self-priming from minus-strand strong-stop DNA.

During the first strand transfer in reverse transcription, minus-strand strong-stop DNA [(-) SSDNA] is annealed to the 3' end of the acceptor RNA in a reaction mediated by base-pairing between terminal repeat sequences in the RNA and their complement in the DNA. The large stem-loop structure in...

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Main Authors: Guo, J, Henderson, L E, Bess, J, Kane, B, Levin, J G
פורמט: Artigo
שפה:Inglês
יצא לאור: 1997
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC191753/
https://ncbi.nlm.nih.gov/pubmed/9188585
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