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Pharmacokinetic-pharmacodynamic modelling of the anticonvulsant effect of oxazepam in individual rats.

1. The purpose of this investigation was to examine in vivo drug-concentration anticonvulsant effect relationships of oxazepam in individual rats following administration of a single dose. 2. Whole blood concentration vs time profiles of oxazepam were determined following administration of doses of...

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Hlavní autoři: Dingemanse, J., Voskuyl, R. A., Langemeijer, M. W., Postel-Westra, I., Breimer, D. D., Meinardi, H., Danhof, M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917521/
https://ncbi.nlm.nih.gov/pubmed/2331575
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