Pharmacodynamics of the anticonvulsant effect of oxazepam in aging BN/BiRij rats.

1. The purpose of this investigation was to examine the influence of increasing age on the pharmacokinetics and the time course of the anticonvulsant response of oxazepam in BN/BiRij rats as an animal model of aging. 2. Oxazepam was administered intravenously in a dose of 12 mg kg-1 body weight and...

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Hauptverfasser: Stijnen, A. M., Postel-Westra, I., Langemeijer, M. W., Hoogerkamp, A., Voskuyl, R. A., van Bezooijen, C. F., Danhof, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907588/
https://ncbi.nlm.nih.gov/pubmed/1330159
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