Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse.

1. The injection of 100 or 300 micrograms of carrageenin into the mouse paw or pleural cavity produced a delayed inflammatory reaction at 48 h while platelet activating factor (PAF)-induced paw oedema and pleurisy were maximal 30 min after its injection. 2. The PAF antagonist, WEB 2086, failed to in...

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Main Authors: Henriques, M. G., Weg, V. B., Martins, M. A., Silva, P. M., Fernandes, P. D., Cordeiro, R. S., Vargaftig, B. B.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917491/
https://ncbi.nlm.nih.gov/pubmed/2331569
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