Long-lasting inhibitory activity of the hetrazepinic BN 50730 on exudation and cellular alterations evoked by PAF and LPS.

1. Inhibitory effects of the hetrazepinic derivative BN 50730 on the rat pleural inflammatory response, triggered by PAF or lipopolysaccharides (LPS), were examined. The type of pharmacological blockade exerted by this antagonist in in vitro assays of eosinophil chemotaxis and platelet aggregation w...

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Autori principali: Pires, A L, e Silva, P M, Pasquale, C, Castro-Faria-Neto, H C, Bozza, P T, Cordeiro, R S, Rae, G A, Braquet, P, Lagente, V, Martins, M A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1510468/
https://ncbi.nlm.nih.gov/pubmed/7858896
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