2-substituted indazolinones: orally active and selective 5-lipoxygenase inhibitors with anti-inflammatory activity.

1. This paper describes the pharmacological profile of ICI207968, a novel, orally-active and selective inhibitor of 5-lipoxygenase. 2. Inhibition of leukotriene B4 (LTB4) synthesis by 2-substituted indazolinones was not directly related to redox potential but was critically dependent on the nature o...

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Detaylı Bibliyografya
Asıl Yazarlar: Foster, S. J., Bruneau, P., Walker, E. R., McMillan, R. M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1990
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917488/
https://ncbi.nlm.nih.gov/pubmed/2110012
Etiketler: Etiketle
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