Transcriptional targeting of herpes simplex virus for cell-specific replication.
Tissue- or cell-specific targeting of vectors is critical to the success of gene therapy. We describe a novel approach to virus-mediated gene therapy, where viral replication and associated cytotoxicity are limited to a specific cell type by the regulated expression of an essential immediate-early v...
Enregistré dans:
| Publié dans: | J Virol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188579/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5124-5132.1997 |
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