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Transcriptional targeting of herpes simplex virus for cell-specific replication.

Tissue- or cell-specific targeting of vectors is critical to the success of gene therapy. We describe a novel approach to virus-mediated gene therapy, where viral replication and associated cytotoxicity are limited to a specific cell type by the regulated expression of an essential immediate-early v...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Miyatake, S, Iyer, A, Martuza, R L, Rabkin, S D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1997
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191747/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5124-5132.1997
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