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Mapping a disease locus by allelic association

Allelic association provides a means to map disease genes that, in a dense map of polymorphic markers, has considerably higher resolution than linkage methods. We describe here a composite likelihood estimate of location for a disease gene against a high-resolution marker map by using allele frequen...

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Bibliografske podrobnosti
Main Authors: Collins, A., Morton, N. E.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC19174/
https://ncbi.nlm.nih.gov/pubmed/9465087
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