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Mapping a disease locus by allelic association

Allelic association provides a means to map disease genes that, in a dense map of polymorphic markers, has considerably higher resolution than linkage methods. We describe here a composite likelihood estimate of location for a disease gene against a high-resolution marker map by using allele frequen...

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Autori principali: Collins, A., Morton, N. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC19174/
https://ncbi.nlm.nih.gov/pubmed/9465087
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