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Effects of chain-length and unsaturation on affinity and selectivity at muscarinic receptors.

1. Lengthening the chain in diphenylacetylcholine decreases affinity for muscarinic cholinoceptors in guinea-pig ileum. Diphenylacetoxypropyldimethylamine and its quaternary trimethylammonium salt are roughly equiactive: the dimethylamine and the piperidine have some selectivity for ileum compared w...

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Bibliografski detalji
Glavni autori: Barlow, R. B., Holdup, D. W., Harris, G., Veale, M. A., Williams, A.
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917351/
https://ncbi.nlm.nih.gov/pubmed/2331586
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