Effects of 5-hydroxy-propafenone in guinea-pig atrial fibres.

The effects of 5-hydroxy-propafenone (5-OH-P), an active metabolite of propafenone, were studied on isolated atrial muscle fibres obtained from non-treated guinea-pigs and from animals pretreated with 5-OH-P, 3 mg kg-1, for 28 days. In untreated atria 5-OH-P, 10(-8) M-10(-4) M, produced a dose-depen...

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Главные авторы: Delgado, C., Tamargo, J., Tejerina, T., Valenzuela, C.
Формат: Artigo
Язык:Inglês
Опубликовано: 1987
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917170/
https://ncbi.nlm.nih.gov/pubmed/2882804
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