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Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line.

We report here the construction of a new packaging cell line, called MPAC, that packages defective retroviral vectors in viral particles with envelope proteins derived from a Moloney mink cell focus-inducing (MCF) polytropic virus. We characterized the tropism of MPAC-packaged retroviral vectors and...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Loiler, S A, DiFronzo, N L, Holland, C A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191707/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151879/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4825-4828.1997
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