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Electrical and mechanical effects of BRL34915 in guinea-pig isolated trachealis.

BRL34915 (0.1-10 microM) suppressed the spontaneous tone of guinea-pig isolated trachealis in a concentration-dependent manner. BRL34915 was not antagonized by propranolol (1 microM). In trachea where spontaneous tone was suppressed by indomethacin (2.8 microM) but subsequently restored to the same...

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Bibliographic Details
Main Authors: Allen, S. L., Boyle, J. P., Cortijo, J., Foster, R. W., Morgan, G. P., Small, R. C.
Format: Artigo
Language:Inglês
Published: 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1917004/
https://ncbi.nlm.nih.gov/pubmed/2430658
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