Mechanical and electrical aspects of the relaxant action of aminophylline in guinea-pig isolated trachealis.

Aminophylline (1-1000 mumol l-1) suppressed the spontaneous tone of guinea-pig isolated trachealis in a concentration-dependent manner. In Krebs solution containing acetylcholine (1 mmol l-1), histamine (200 mumol l-1) or K+ (120 mmol l-1) isolated trachealis muscle developed near-maximal tension. T...

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Bibliographic Details
Main Authors: Allen, S. L., Cortijo, J., Foster, R. W., Morgan, G. P., Small, R. C., Weston, A. H.
Format: Artigo
Language:Inglês
Published: 1986
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916826/
https://ncbi.nlm.nih.gov/pubmed/3730702
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