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Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet-activating factor is mediated by leukotriene C4.

Platelet-activating factor (Paf, 0.04-4.50 nmol) dose-dependently induced coronary vasoconstriction and decreased cardiac contractility in rat, isolated perfused hearts and concomitantly released leukotriene-like bioactivity into the cardiac effluent. Platelet-activating factor (0.9 nmol) induced an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Piper, P. J., Stewart, A. G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916979/
https://ncbi.nlm.nih.gov/pubmed/3091131
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