Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology.

The human immunodeficiency virus type 1 (HIV-1) Vpr protein prevents infected cells from passing through mitosis by arresting them in the G2 phase of the cell cycle. Vpr is conserved among all primate lentiviruses, suggesting an important role in the virus life cycle. Moreover, in this study we show...

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Argitaratua izan da:	J Virol
Egile Nagusiak:	Stivahtis, G L, Soares, M A, Vodicka, M A, Hahn, B H, Emerman, M
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1997
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191649/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4331-4338.1997
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