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Human immunodeficiency virus type 1 Vpr induces apoptosis following cell cycle arrest.

The human immunodeficiency virus type 1 (HIV-1) vpr gene encodes a protein which induces arrest of cells in the G2 phase of the cell cycle. Here, we demonstrate that following the arrest of cells in G2, Vpr induces apoptosis in human fibroblasts, T cells, and primary peripheral blood lymphocytes. An...

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Udgivet i:J Virol
Principais autores: Stewart, S A, Poon, B, Jowett, J B, Chen, I S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191800/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188632/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5579-5592.1997
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