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Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase

Conjugative transfer of plasmid DNA via close cell–cell junctions is the main route by which antibiotic resistance genes spread between bacterial strains. Relaxases are essential for conjugative transfer and act by cleaving DNA strands and forming covalent phosphotyrosine linkages. Based on data ind...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lujan, Scott A., Guogas, Laura M., Ragonese, Heather, Matson, Steven W., Redinbo, Matthew R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1916486/
https://ncbi.nlm.nih.gov/pubmed/17630285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702760104
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