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Disrupting antibiotic resistance propagation by inhibiting the conjugative DNA relaxase
Conjugative transfer of plasmid DNA via close cell–cell junctions is the main route by which antibiotic resistance genes spread between bacterial strains. Relaxases are essential for conjugative transfer and act by cleaving DNA strands and forming covalent phosphotyrosine linkages. Based on data ind...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1916486/ https://ncbi.nlm.nih.gov/pubmed/17630285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702760104 |
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