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Characterization of molecularly cloned simian-human immunodeficiency viruses causing rapid CD4+ lymphocyte depletion in rhesus monkeys.

In vivo passage of a chimeric simian-human immunodeficiency virus (SHIV-89.6) expressing the human immunodeficiency virus type 1 (HIV-1) tat, rev, vpu, and env genes generated pathogenic viruses (SHIV-89.6P) inducing rapid CD4+ lymphocyte depletion and AIDS-like illness in rhesus monkeys (K. Reimann...

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Published in:J Virol
Main Authors: Karlsson, G B, Halloran, M, Li, J, Park, I W, Gomila, R, Reimann, K A, Axthelm, M K, Iliff, S A, Letvin, N L, Sodroski, J
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191636/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9151808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.6.4218-4225.1997
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