An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys.

To explore the roles played by specific human immunodeficiency virus type 1 (HIV-1) genes in determining the in vivo replicative capacity of AIDS viruses, we have examined the replication kinetics and virus-specific immune responses in rhesus monkeys following infection with two chimeric simian/huma...

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Main Authors: Reimann, K A, Li, J T, Voss, G, Lekutis, C, Tenner-Racz, K, Racz, P, Lin, W, Montefiori, D C, Lee-Parritz, D E, Lu, Y, Collman, R G, Sodroski, J, Letvin, N L
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC190183/
https://ncbi.nlm.nih.gov/pubmed/8627800
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