Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum.
Quinine and quinidine were over 100 times more active than 9-epiquinine and 9-epiquinidine against chloroquine-sensitive Plasmodium falciparum and over 10 times more active against chloroquine-resistant P. falciparum. Since the only structural difference between quinine, quinidine, 9-epiquinine, and...
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| 發表在: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
1992
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1510452/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.7.1538 |
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