Use of D gene segments with irregular spacers in terminal deoxynucleotidyltransferase (TdT)(+/+) and TdT(−/−) mice carrying a human Ig heavy chain transgenic minilocus
D gene segments with irregular spacers (DIR) are D gene segments that are specific to higher primates. Their use is controversial because of their G+C-rich long sequences. In the human, it has always been tempting to assume that a complementarity-determining region 3 sequence has been added by termi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19158/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9465080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.4.1703 |
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