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Effects of cytochrome P450 inhibitors on potassium currents and mechanical activity in rat portal vein.

1. The effects of the cytochrome P450 inhibitors, proadifen, clotrimazole and 17-octadecynoic acid (17-ODYA) on K-currents in freshly-isolated single cells derived from rat portal vein and on mechanical activity in whole veins were studied. 2. When cells were stepped from -90 mV to a series of test...

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Bibliographic Details
Main Authors: Edwards, G., Zygmunt, P. M., Högestätt, E. D., Weston, A. H.
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1915770/
https://ncbi.nlm.nih.gov/pubmed/8904643
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