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Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery.

1. The possibility that the endothelium-derived hyperpolarising factor (EDHF) in the rat hepatic artery is a cytochrome P450 mono-oxygenase metabolite of arachidonic acid was examined in the present study. In this preparation, acetylcholine elicits EDHF-mediated relaxations in the presence of the ni...

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Detalhes bibliográficos
Main Authors: Zygmunt, P. M., Edwards, G., Weston, A. H., Davis, S. C., Högestätt, E. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1909609/
https://ncbi.nlm.nih.gov/pubmed/8818337
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