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The poly(C) region affects progression of encephalomyocarditis virus infection in Langerhans' islets but not in the myocardium.

The diabetogenic variant PV2 of encephalomyocarditis virus was cloned, and three recombinants differing in their 5' poly(C) tracts were analyzed. It is shown that the poly(C) region is not essential for infectivity in mice but does influence the virus load and degree of pathological lesions within t...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Zimmermann, A, Botta, A, Arnold, G, Eggers, H J, Nelsen-Salz, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191573/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.4145-4149.1997
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