Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1.

The condition of a chimpanzee (C499) infected with three different isolates of human immunodeficiency virus type 1 (HIV-1) for over 10 years progressed to AIDS. Disease development in this animal was characterized by (i) a decline in CD4+ cells over the last 3 years; (ii) an increase in viral loads...

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Main Authors: Novembre, F J, Saucier, M, Anderson, D C, Klumpp, S A, O'Neil, S P, Brown, C R, Hart, C E, Guenthner, P C, Swenson, R B, McClure, H M
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191562/
https://ncbi.nlm.nih.gov/pubmed/9094687
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