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Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors
Agonist exposure can cause internalisation of G-protein coupled receptors (GPCRs), which may be a part of desensitisation but also of cellular signaling. Previous methods to study internalisation have been tedious or only poorly quantitative. Therefore, we have developed and validated a quantitative...
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Main Authors: | , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Springer-Verlag
2007
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1915601/ https://ncbi.nlm.nih.gov/pubmed/17497135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-007-0164-8 |
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