Potent inhibition of human immunodeficiency virus type 1 in primary T cells and alveolar macrophages by a combination anti-Rev strategy delivered in an adeno-associated virus vector.

The rate of viral replication appears to play a pivotal role in human immunodeficiency virus type 1 (HIV-1) pathogenesis and disease progression as it outstrips the capacity of the immune system to respond. Important cellular sites for HIV-1 production include T lymphocytes and tissue macrophages. A...

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Bibliographic Details
Main Authors: Inouye, R T, Du, B, Boldt-Houle, D, Ferrante, A, Park, I W, Hammer, S M, Duan, L, Groopman, J E, Pomerantz, R J, Terwilliger, E F
Format: Artigo
Language:Inglês
Published: 1997
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191560/
https://ncbi.nlm.nih.gov/pubmed/9094685
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