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A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families.

We have analyzed 20 breast-ovarian cancer families, the majority of which show positive evidence of linkage to chromosome 17q12 for germ-line mutations in the BRCA1 gene. BRCA1 mutations cosegregating with breast and ovarian cancer susceptibility were identified in 16 families, including 1 family wi...

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Bibliografiske detaljer
Main Authors: Serova, O., Montagna, M., Torchard, D., Narod, S. A., Tonin, P., Sylla, B., Lynch, H. T., Feunteun, J., Lenoir, G. M.
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914944/
https://ncbi.nlm.nih.gov/pubmed/8554067
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