Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test.
Dopaminergic abnormalities are implicated in the pathogenesis of Tourette syndrome (TS) and chronic multiple tics. We used the transmission-disequilibrium test (TDT) method to test for linkage disequilibrium between a specific allele (the seven-repeat allele (DRD4*7R) of the exon 3 VNTR polymorphic...
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Glavni autori: | , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1996
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914894/ https://ncbi.nlm.nih.gov/pubmed/8751866 |
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