Linkage disequilibrium between an allele at the dopamine D4 receptor locus and Tourette syndrome, by the transmission-disequilibrium test.

Dopaminergic abnormalities are implicated in the pathogenesis of Tourette syndrome (TS) and chronic multiple tics. We used the transmission-disequilibrium test (TDT) method to test for linkage disequilibrium between a specific allele (the seven-repeat allele (DRD4*7R) of the exon 3 VNTR polymorphic...

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Main Authors: Grice, D. E., Leckman, J. F., Pauls, D. L., Kurlan, R., Kidd, K. K., Pakstis, A. J., Chang, F. M., Buxbaum, J. D., Cohen, D. J., Gelernter, J.
Formato: Artigo
Idioma:Inglês
Publicado: 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914894/
https://ncbi.nlm.nih.gov/pubmed/8751866
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