Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization.

A stem-loop termed the kissing-loop hairpin is one of the most highly conserved structures within the leader of human immunodeficiency virus type 1 (HIV-1) and chimpanzee immunodeficiency virus genomic RNA. Because it plays a key role in the in vitro dimerization of short HIV-1 RNA transcripts (M. L...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Laughrea, M, Jetté, L, Mak, J, Kleiman, L, Liang, C, Wainberg, M A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3397-3406.1997
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