Mutations in the kissing-loop hairpin of human immunodeficiency virus type 1 reduce viral infectivity as well as genomic RNA packaging and dimerization.

A stem-loop termed the kissing-loop hairpin is one of the most highly conserved structures within the leader of human immunodeficiency virus type 1 (HIV-1) and chimpanzee immunodeficiency virus genomic RNA. Because it plays a key role in the in vitro dimerization of short HIV-1 RNA transcripts (M. L...

Full description

Saved in:
Bibliographic Details
Main Authors: Laughrea, M, Jetté, L, Mak, J, Kleiman, L, Liang, C, Wainberg, M A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC191484/
https://ncbi.nlm.nih.gov/pubmed/9094609
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items