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Analysis of meiotic segregation, using single-sperm typing: meiotic drive at the myotonic dystrophy locus.

Meiotic drive at the myotonic dystrophy (DM) locus has recently been suggested as being responsible for maintaining the frequency, in the human population, of DM chromosomes capable of expansion to the disease state. In order to test this hypothesis, we have studied samples of single sperm from thre...

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Detalhes bibliográficos
Main Authors: Leeflang, E. P., McPeek, M. S., Arnheim, N.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914809/
https://ncbi.nlm.nih.gov/pubmed/8808606
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