Differences in sialic acid-galactose linkages in the chicken egg amnion and allantois influence human influenza virus receptor specificity and variant selection.

Human influenza viruses are more efficiently isolated by inoculating patient samples into the amniotic rather than the allantoic cavity of embryonated chicken eggs. This type of cultivation selects virus variants with mutations around the hemagglutinin (HA) receptor binding site. To understand the m...

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Autori principali: Ito, T, Suzuki, Y, Takada, A, Kawamoto, A, Otsuki, K, Masuda, H, Yamada, M, Suzuki, T, Kida, H, Kawaoka, Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC191479/
https://ncbi.nlm.nih.gov/pubmed/9060710
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