The cellular YY1 transcription factor binds a cis-acting, negatively regulating element in the Epstein-Barr virus BRLF1 promoter.

Disruption of Epstein-Barr virus latency is induced by expression of either the BZLF1 (in B cells and epithelial cells) or BRLF1 (in epithelial cells only) immediate-early protein. Regulation of BZLF1 and BRLF1 transcription may therefore modulate the stringency of viral latency. The cellular transc...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zalani, S, Coppage, A, Holley-Guthrie, E, Kenney, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060693/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3268-3274.1997
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