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The cellular YY1 transcription factor binds a cis-acting, negatively regulating element in the Epstein-Barr virus BRLF1 promoter.

Disruption of Epstein-Barr virus latency is induced by expression of either the BZLF1 (in B cells and epithelial cells) or BRLF1 (in epithelial cells only) immediate-early protein. Regulation of BZLF1 and BRLF1 transcription may therefore modulate the stringency of viral latency. The cellular transc...

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Bibliografische gegevens
Hoofdauteurs: Zalani, S, Coppage, A, Holley-Guthrie, E, Kenney, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC191462/
https://ncbi.nlm.nih.gov/pubmed/9060693
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