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Molecular Mechanism of the Zn(2+)-Induced Folding of the Distal CCHC Finger Motif of the HIV-1 Nucleocapsid Protein
HIV-1 nucleocapsid protein, NCp7, contains two highly conserved CCHC zinc fingers. Binding of Zn(2+) drives NCp7 from an unfolded to a highly folded structure that is critical for its functions. Using the intrinsic fluorescence of Trp(37), we investigated, by the stopped-flow technique, the folding...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Biophysical Society
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914429/ https://ncbi.nlm.nih.gov/pubmed/17416621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.101378 |
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