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Sarcomere Lattice Geometry Influences Cooperative Myosin Binding in Muscle

In muscle, force emerges from myosin binding with actin (forming a cross-bridge). This actomyosin binding depends upon myofilament geometry, kinetics of thin-filament Ca(2+) activation, and kinetics of cross-bridge cycling. Binding occurs within a compliant network of protein filaments where there i...

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Detalhes bibliográficos
Main Authors: Tanner, Bertrand C. W, Daniel, Thomas L, Regnier, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914368/
https://ncbi.nlm.nih.gov/pubmed/17630823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030115
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