Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes

BACKGROUND: Physiological long term adaptation of pancreatic beta cells is driven by stimuli such as glucose and incretin hormones acting via cAMP (e.g. GLP-1) and involves regulated gene expression. Several rapidly inducible immediate-early genes (IEGs) have been identified in beta cells. Many of t...

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Detaylı Bibliyografya
Asıl Yazarlar: Glauser, Dominique A, Brun, Thierry, Gauthier, Benoit R, Schlegel, Werner
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914353/
https://ncbi.nlm.nih.gov/pubmed/17587450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-54
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