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Load-dependent release limits the processive stepping of the tetrameric Eg5 motor
Tetrameric motor proteins of the Kinesin-5 family are essential for eukaryotic cell division. The microscopic mechanism by which Eg5, the vertebrate Kinesin-5, drives bipolar mitotic spindle formation remains unknown. Here we show in optical trapping experiments that full-length Eg5 moves processive...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer-Verlag
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914257/ https://ncbi.nlm.nih.gov/pubmed/17333163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-007-0134-6 |
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