Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease

In humans, complex I of the respiratory chain is composed of seven mitochondrial DNA (mtDNA)-encoded and 38 nuclear-encoded subunits that assemble together in a process that is poorly defined. To date, only two complex I assembly factors have been identified and how each functions is not clear. Here...

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Autori principali: Dunning, C J R, McKenzie, M, Sugiana, C, Lazarou, M, Silke, J, Connelly, A, Fletcher, J M, Kirby, D M, Thorburn, D R, Ryan, M T
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914096/
https://ncbi.nlm.nih.gov/pubmed/17557076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601748
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